Within the transitional phase of CISE, the CISE Stakeholder Group initiates Test Campaigns, with the main goal to test the connectivity and overall operability of the CISE network. Following the successful first Test Campaign in spring of 2020, the second Test Campaign was performed from October to December with the aim to further increase the involvement of node owning countries and to test additional services. The activity was carefully prepared by a dedicated Task Force of stakeholders and included the nodes from Finland, Bulgaria, Spain, Italy, Portugal and Greece. Minor issues encountered during the tests will be followed up. The outcome of the campaign demonstrated a good level of overall health of the network and of stakeholder commitment.